New trials show that a male contraceptive gel, applied daily to the shoulders, works faster than similar injections and is both safe and effective. This innovative gel, designed to reduce sperm count, offers a quicker onset of action compared to other methods, making it a promising option for male birth control.
Research indicates that the gel lowers sperm count to contraceptive levels within an average of eight weeks, significantly faster than the nine to 15 weeks required for male contraceptive injections. Researchers from the Contraceptive Development Programme at the US National Institutes of Health (NIH) believe this faster efficacy could increase its appeal among men.
In the trial, 222 men applied 5ml of the gel – approximately a teaspoon – to each shoulder blade daily. The gel combines two hormones: testosterone and a synthetic hormone called Nestorone. While testosterone alone can reduce sperm count, the addition of Nestorone accelerates the process and allows for lower doses of testosterone, minimising side effects such as reduced sex drive.
Currently, the gel is the most advanced among new male birth control options, though it is still undergoing trials. Logan Whitehead, 24, participated in the trial and expressed his willingness to continue using the gel if it becomes available, especially after seeing his partner struggle with existing female contraceptive methods. “The gel was such an easy process,” Whitehead told NBC News. “It was basically like taking the pill for the day.”
Whitehead reported minimal side effects, including some upper back acne and potential weight gain, which could also be attributed to a new sedentary job. Researchers are continuing to evaluate the gel’s effectiveness in preventing pregnancy, its safety, acceptability, and how quickly fertility returns after stopping the gel.
However, funding is currently lacking for the crucial phase three trials necessary for drug approval. Dr Brian Nguyen, a gynaecologist and investigator on the gel trial, mentioned the need for significant investment from a major pharmaceutical company to advance the trials. Despite the desire for male contraceptive options, many couples still rely on female birth control.
“People always ask, ‘How long will it be until we see this product on the market?'” Dr Nguyen said. “Most people will say five to 10 years, but I disagree.”
The future of this male contraceptive gel depends on further research and funding to bring it to market, potentially offering a new and effective birth control option for men.
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